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Substrate Binding to Cytochromes P450

P450s have attracted tremendous attention due not only to their involvement in the metabolism of drug molecules and endogenous substrates but also the unusual nature of the reaction they catalyze, namely the oxidation of unactivated C-H bonds. The binding of substrates to P450s, which is usually vie...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Isin, Emre M., Guengerich, F. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756639/
https://ncbi.nlm.nih.gov/pubmed/18622598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-008-2244-0
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