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Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants

M01A82W, M11A82W and M01A82WS72I are three cytochrome P450 BM3 (CYP102A1) variants. They can catalyze the hydroxylation of testosterone (TES) and norethisterone at different positions, thereby making them promising biocatalysts for steroid hydroxylation. With the aim of obtaining more hydroxylated s...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Liu, Xing, Wang, Zhi-Biao, Wang, Ya-Nan, Kong, Jian-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273762/
https://ncbi.nlm.nih.gov/pubmed/27294908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21060760
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