The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes

Por Bahjat, Mahnoush, Guikema, Jeroen E. J.
Publicado no Int J Mol Sci (2017)

Mechanism and Regulation of Class Switch Recombination

Por Stavnezer, Janet, Guikema, Jeroen E.J., Schrader, Carol E.
Publicado em 2008

The roles of APE1, APE2, DNA polymerase β and mismatch repair in creating S region DNA breaks during antibody class switch

Por Schrader, Carol E., Guikema, Jeroen E.J., Wu, Xiaoming, Stavnezer, Janet
Publicado em 2008

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig loci in activated B cells

Por Staszewski, Ori, Baker, Richard E., Ucher, Anna J., Martier, Raygene, Stavnezer, Janet, Guikema, Jeroen E.J.
Publicado em 2011

A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase β

Por Pei, De-Sheng, Yang, Xiao-Jie, Liu, Wei, Guikema, Jeroen E. J., Schrader, Carol E., Strauss, Phyllis R.
Publicado em 2011

AP endonuclease 2 regulates the expansion of germinal centers by protecting against AID-independent DNA damage in B cells()

Por Guikema, Jeroen E.J., Linehan, Erin K., Esa, Nada, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Woodland, Robert T., Schrader, Carol E.
Publicado em 2014

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Por Bahjat, Mahnoush, Bloedjes, Timon A., van der Veen, Amélie, de Wilde, Guus, Maas, Chiel, Guikema, Jeroen E. J.
Publicado no J Vis Exp (2017)

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination

Por Guikema, Jeroen E.J., Linehan, Erin K., Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Strauss, Phyllis R., Stavnezer, Janet, Schrader, Carol E.
Publicado em 2007

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination

Por Guikema, Jeroen E.J., Linehan, Erin K., Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Strauss, Phyllis R., Stavnezer, Janet, Schrader, Carol E.
Publicado em 2007

Identification of a novel stereotypic IGHV4-59/IGHJ5-encoded B-cell receptor subset expressed by various B-cell lymphomas with high affinity rheumatoid factor activity

Por Bende, Richard J., Janssen, Jerry, Wormhoudt, Thera A.M., Wagner, Koen, Guikema, Jeroen E.J., van Noesel, Carel J.M.
Publicado no Haematologica (2016)

Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching

Por Guikema, Jeroen E. J., Schrader, Carol E., Leus, Niek G. J., Ucher, Anna, Linehan, Erin K., Werling, Uwe, Edelmann, Winfried, Stavnezer, Janet
Publicado em 2008

AP-Endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge

Por Guikema, Jeroen E.J., Gerstein, Rachel M., Linehan, Erin K., Cloherty, Erin K., Evan-Browning, Eric, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Schrader, Carol E.
Publicado em 2011

ATM increases AID activity at downstream S regions during class switch recombination

Por Khair, Lyne, Guikema, Jeroen E.J., Linehan, Erin K., Ucher, Anna J., Leus, Niek G.J., Ogilvie, Colin, Lou, Zhenkun, Schrader, Carol E., Stavnezer, Janet
Publicado em 2014

NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity

Por Ochodnicka-Mackovicova, Katarina, Bahjat, Mahnoush, Bloedjes, Timon A., Maas, Chiel, de Bruin, Alexander M., Bende, Richard J., van Noesel, Carel J. M., Guikema, Jeroen E. J.
Publicado no Blood (2015)

p53 Represses Class Switch Recombination to IgG2a through its Antioxidant Function

Por Guikema, Jeroen E.J., Schrader, Carol E., Brodsky, Michael H., Linehan, Erin K., Richards, Adam, El Falaky, Nahla, Li, Daniel H., Sluss, Hayla K., Szomolanyi-Tsuda, Eva, Stavnezer, Janet
Publicado em 2010

Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing

Por Reshetova, Polina, van Schaik, Barbera D. C., Klarenbeek, Paul L., Doorenspleet, Marieke E., Esveldt, Rebecca E. E., Tak, Paul-Peter, Guikema, Jeroen E. J., de Vries, Niek, van Kampen, Antoine H. C.
Publicado no Front Immunol (2017)

A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi

Por Hoogeboom, Robbert, van Kessel, Kok P.M., Hochstenbach, Frans, Wormhoudt, Thera A., Reinten, Roy J.A., Wagner, Koen, Kater, Arnon P., Guikema, Jeroen E.J., Bende, Richard J., van Noesel, Carel J.M.
Publicado em 2013

Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins

Por van Andel, Harmen, Ren, Zemin, Koopmans, Iris, Joosten, Sander P. J., Kocemba, Kinga A., de Lau, Wim, Kersten, Marie José, de Bruin, Alexander M., Guikema, Jeroen E. J., Clevers, Hans, Spaargaren, Marcel, Pals, Steven T.
Publicado no Proc Natl Acad Sci U S A (2017)

Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model

Por Lascano, Valeria, Guadagnoli, Marco, Schot, Jan G., Luijks, Dieuwertje M., Guikema, Jeroen E. J., Cameron, Katherine, Hahne, Michael, Pals, Steven, Slinger, Erik, Kipps, Thomas J., van Oers, Marinus H. J., Eldering, Eric, Medema, Jan Paul, Kater, Arnon P.
Publicado em 2013