BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy

по Ramesh, Prashanthi, Medema, Jan Paul
Опубликовано в: Apoptosis (2020)

Intra-tumor heterogeneity from a cancer stem cell perspective

по Prasetyanti, Pramudita R., Medema, Jan Paul
Опубликовано в: Mol Cancer (2017)

Molecular identification and targeting of colorectal cancer stem cells

по Kemper, Kristel, Grandela, Catarina, Medema, Jan Paul
Опубликовано 2010

Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF

по Fessler, Evelyn, Borovski, Tijana, Medema, Jan Paul
Опубликовано в: Mol Cancer (2015)

Axing Wnt signals

по De Sousa E Melo, Felipe, Medema, Jan Paul
Опубликовано 2012

Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges

по Buikhuisen, Joyce Y., Torang, Arezo, Medema, Jan Paul
Опубликовано в: Oncogenesis (2020)

Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol

по Mullauer, Franziska B., Kessler, Jan H., Medema, Jan Paul
Опубликовано 2009

BH3 Mimetic Sensitivity of Colorectal Cancer Cell Lines in Correlation with Molecular Features Identifies Predictors of Response

по Zhang, Le, Ramesh, Prashanthi, Steinmetz, Maxime, Medema, Jan Paul
Опубликовано в: Int J Mol Sci (2021)

Mouse Tissues Express Multiple Splice Variants of Prominin-1

по Kemper, Kristel, Tol, Marc J. P. M., Medema, Jan Paul
Опубликовано 2010

Targeting colorectal cancer stem cells with inducible caspase-9

по Kemper, Kristel, Rodermond, Hans, Colak, Selçuk, Grandela, Catarina, Medema, Jan Paul
Опубликовано 2012

Cancer heterogeneity—a multifaceted view

по Melo, Felipe De Sousa E, Vermeulen, Louis, Fessler, Evelyn, Medema, Jan Paul
Опубликовано 2013

Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein

по Medema, Jan Paul, de Jong, Joan, van Hall, Thorbald, Melief, Cornelis J.M., Offringa, Rienk
Опубликовано 1999

Assessment of the stromal contribution to Sonic Hedgehog‐dependent pancreatic adenocarcinoma

по Damhofer, Helene, Medema, Jan Paul, Veenstra, Veronique L., Badea, Liviu, Popescu, Irinel, Roelink, Henk, Bijlsma, Maarten F.
Опубликовано 2013

Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon

по Prasetyanti, Pramudita Ramadhina, Zimberlin, Cheryl Doreen, Bots, Michael, Vermeulen, Louis, De Sousa E Melo, Felipe, Medema, Jan Paul
Опубликовано 2013

CD44 Expression in Intestinal Epithelium and Colorectal Cancer Is Independent of p53 Status

по Zeilstra, Jurrit, Joosten, Sander P. J., Vermeulen, Louis, Koster, Jan, Medema, Jan Paul, Versteeg, Rogier, Spaargaren, Marcel, Pals, Steven T.
Опубликовано 2013

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: Interrelationships and clinical implications

по Sadanandam, Anguraj, Wang, Xin, de Sousa E Melo, Felipe, Gray, Joe W, Vermeulen, Louis, Hanahan, Douglas, Medema, Jan Paul
Опубликовано 2014

Cyclopentenylcytosine does not enhance cisplatin-induced radiosensitization in human lung tumour cells

по RODERMOND, HANS M., CATE, ROSEMARIE TEN, HAVEMAN, JAAP, VAN KUILENBURG, ANDRÉ, MEDEMA, JAN PAUL, VAN BREE, CHRIS, FRANKEN, NICOLAAS A.P.
Опубликовано 2010

GRANZYME A AND B-CLUSTER DEFICIENCY DELAYS ACUTE LUNG INJURY IN PNEUMOVIRUS-INFECTED MICE

по Bem, Reinout A., van Woensel, Job B.M., Lutter, Rene, Domachowske, Joseph B., Medema, Jan Paul, Rosenberg, Helene F., Bos, Albert P.
Опубликовано 2009

Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia

по García-Laorden, M. Isabel, Stroo, Ingrid, Blok, Dana C., Florquin, Sandrine, Medema, Jan Paul, de Vos, Alex F., van der Poll, Tom
Опубликовано в: J Innate Immun (2016)

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment

по van Oorschot, Bregje, Granata, Giovanna, Di Franco, Simone, Cate, Rosemarie ten, Rodermond, Hans M., Todaro, Matilde, Medema, Jan Paul, Franken, Nicolaas A.P.
Опубликовано в: Oncotarget (2016)