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BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy

Apoptosis is a form of programmed cell death that is essential for tissue homeostasis. De-regulation of the balance between proliferation and apoptosis contributes to tumor initiation. Particularly in the colon where apoptosis is a crucial process in intestinal turnover, inhibition of apoptosis faci...

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Detalhes bibliográficos
Publicado no:Apoptosis
Main Authors: Ramesh, Prashanthi, Medema, Jan Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244464/
https://ncbi.nlm.nih.gov/pubmed/32335811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-020-01601-9
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