Defining the susceptibility of colorectal cancers to BH3-mimetic compounds

Novel targets are required to improve the outcomes for patients with colorectal cancers. In this regard, the selective inhibitor of the pro-survival protein BCL2, venetoclax, has proven highly effective in several hematological malignancies. In addition to BCL2, potent and highly selective small mol...

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Luo, Ming-Jie, Palmieri, Michelle, Riffkin, Chris D., Sakthianandeswaren, Anuratha, Djajawi, Tirta Mario, Hirokawa, Yumiko, Shuttleworth, Victoria, Segal, David H., White, Christine A., Nhu, Duong, Lessene, Guillaume, Lee, Margaret, Gibbs, Peter, Huang, David C. S., Sieber, Oliver M., Gong, Jia-nan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483443/
https://ncbi.nlm.nih.gov/pubmed/32913182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02815-0
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