Defining the susceptibility of colorectal cancers to BH3-mimetic compounds

Novel targets are required to improve the outcomes for patients with colorectal cancers. In this regard, the selective inhibitor of the pro-survival protein BCL2, venetoclax, has proven highly effective in several hematological malignancies. In addition to BCL2, potent and highly selective small mol...

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書誌詳細
出版年:Cell Death Dis
主要な著者: Luo, Ming-Jie, Palmieri, Michelle, Riffkin, Chris D., Sakthianandeswaren, Anuratha, Djajawi, Tirta Mario, Hirokawa, Yumiko, Shuttleworth, Victoria, Segal, David H., White, Christine A., Nhu, Duong, Lessene, Guillaume, Lee, Margaret, Gibbs, Peter, Huang, David C. S., Sieber, Oliver M., Gong, Jia-nan
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
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オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483443/
https://ncbi.nlm.nih.gov/pubmed/32913182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02815-0
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