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The BCL-2 protein family, BH3-mimetics and cancer therapy
Escape from apoptosis is a key attribute of tumour cells and facilitates chemo-resistance. The ‘BCL-2-regulated' or ‘intrinsic' apoptotic pathway integrates stress and survival signalling to govern whether a cancer cell will live or die. Indeed, many pro-apoptotic members of the BCL-2 fami...
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| Foilsithe in: | Cell Death Differ |
|---|---|
| Main Authors: | , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572872/ https://ncbi.nlm.nih.gov/pubmed/25952548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.50 |
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