CD44 Expression in Intestinal Epithelium and Colorectal Cancer Is Independent of p53 Status

CD44 marks stem cell-like cells in a number of tumour types, including colorectal cancer (CRC), while aberrant CD44 expression conveys increased tumourigenic, invasive, and metastatic potential. Previous data indicate that CD44 is a direct target of p53-mediated transcriptional repression in breast...

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Detalhes bibliográficos
Main Authors: Zeilstra, Jurrit, Joosten, Sander P. J., Vermeulen, Louis, Koster, Jan, Medema, Jan Paul, Versteeg, Rogier, Spaargaren, Marcel, Pals, Steven T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756983/
https://ncbi.nlm.nih.gov/pubmed/24009708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072849
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