Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein

The antiapoptotic protein cellular FLICE (Fas-associated death domain–like IL-1β–converting enzyme) inhibitory protein (cFLIP) protects cells from CD95(APO-1/Fas)-induced apoptosis in vitro and was found to be overexpressed in human melanomas. However, cytotoxic T cell–induced apoptosis, which is cr...

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Hlavní autoři: Medema, Jan Paul, de Jong, Joan, van Hall, Thorbald, Melief, Cornelis J.M., Offringa, Rienk
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1999
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195655/
https://ncbi.nlm.nih.gov/pubmed/10510093
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