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Cellular FLICE-inhibitory protein: an attractive therapeutic target?

Cellular FLIP, also known as FLICE-inhibitory protein, has been identified as an inhibitor of apoptosis triggered by engagement of Death Receptor (DR) such as Fas or TRAIL. c-FLIP is recruited to DR signalling complexes, where it prevents caspase activation. Animal models indicated that c-FLIP plays...

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Bibliografski detalji
Glavni autor: Micheau, Olivier
Format: Artigo
Jezik:Inglês
Izdano: Informa Healthcare 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984612/
https://ncbi.nlm.nih.gov/pubmed/12885274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.7.4.559
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