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Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF

BACKGROUND: Glioblastoma multiforme (GBM) is a rapidly growing malignant brain tumor, which has been reported to be organized in a hierarchical fashion with cancer stem cells (CSCs) at the apex. Recent studies demonstrate that this hierarchy does not follow a one-way route but can be reverted with m...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Fessler, Evelyn, Borovski, Tijana, Medema, Jan Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539660/
https://ncbi.nlm.nih.gov/pubmed/26282129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0420-3
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