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Activated astrocytes enhance the dopaminergic differentiation of stem cells and promote brain repair through bFGF

Astrocytes provide neuroprotective effects against degeneration of dopaminergic (DA) neurons and play a fundamental role in DA differentiation of neural stem cells. Here we show that light illumination of astrocytes expressing engineered channelrhodopsin variant (ChETA) can remarkably enhance the re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Yang, Fan, Liu, Yunhui, Tu, Jie, Wan, Jun, Zhang, Jie, Wu, Bifeng, Chen, Shanping, Zhou, Jiawei, Mu, Yangling, Wang, Liping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284631/
https://ncbi.nlm.nih.gov/pubmed/25517983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6627
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