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GRANZYME A AND B-CLUSTER DEFICIENCY DELAYS ACUTE LUNG INJURY IN PNEUMOVIRUS-INFECTED MICE

Lower respiratory tract infection by the human pneumovirus respiratory syncytial virus is a frequent cause of acute lung injury in children. Severe pneumovirus disease in humans is associated with activation of the granzyme pathway by effector lymphocytes, which may promote pathology by exaggerating...

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Detalhes bibliográficos
Main Authors: Bem, Reinout A., van Woensel, Job B.M., Lutter, Rene, Domachowske, Joseph B., Medema, Jan Paul, Rosenberg, Helene F., Bos, Albert P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803336/
https://ncbi.nlm.nih.gov/pubmed/20018616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903029
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