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Activation of the Granzyme Pathway in Children With Severe Respiratory Syncytial Virus Infection

Granzymes (Grs), serine proteases present in granules of effector lymphocytes, are involved in several host immune responses, including the activation of cell death and inflammatory pathways. The main goal of this study was to determine whether the local cell-mediated Gr pathway is activated during...

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Detalhes bibliográficos
Publicado no:Pediatr Res
Main Authors: Bem, Reinout A, Bos, Albert P, Bots, Michael, Wolbink, Angela M, van Ham, S Marieke, Medema, Jan Paul, Lutter, Rene, van Woensel, Job B M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100119/
https://ncbi.nlm.nih.gov/pubmed/18317234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31816fdc32
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