Activation of the Granzyme Pathway in Children With Severe Respiratory Syncytial Virus Infection

Granzymes (Grs), serine proteases present in granules of effector lymphocytes, are involved in several host immune responses, including the activation of cell death and inflammatory pathways. The main goal of this study was to determine whether the local cell-mediated Gr pathway is activated during...

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Bibliografiska uppgifter
I publikationen:Pediatr Res
Huvudupphovsmän: Bem, Reinout A, Bos, Albert P, Bots, Michael, Wolbink, Angela M, van Ham, S Marieke, Medema, Jan Paul, Lutter, Rene, van Woensel, Job B M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group US 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100119/
https://ncbi.nlm.nih.gov/pubmed/18317234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31816fdc32
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