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Mechanism and Regulation of Class Switch Recombination
Antibody class switching occurs in mature B cells in response to antigen stimulation and costimulatory signals. It occurs by a unique type of intrachromosomal deletional recombination within special G-rich tandem repeated DNA sequences [called switch, or S, regions located upstream of each of the he...
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| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707252/ https://ncbi.nlm.nih.gov/pubmed/18370922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.immunol.26.021607.090248 |
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