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Mechanism and Regulation of Class Switch Recombination

Antibody class switching occurs in mature B cells in response to antigen stimulation and costimulatory signals. It occurs by a unique type of intrachromosomal deletional recombination within special G-rich tandem repeated DNA sequences [called switch, or S, regions located upstream of each of the he...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stavnezer, Janet, Guikema, Jeroen E.J., Schrader, Carol E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707252/
https://ncbi.nlm.nih.gov/pubmed/18370922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.immunol.26.021607.090248
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