DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations

Por Schrader, Carol E., Linehan, Erin K., Ucher, Anna J., Bertocci, Barbara, Stavnezer, Janet
Publicado em 2013

Individual Substitution Mutations in the AID C Terminus That Ablate IgH Class Switch Recombination

Por Kadungure, Tatenda, Ucher, Anna J., Linehan, Erin K., Schrader, Carol E., Stavnezer, Janet
Publicado no PLoS One (2015)

The DNA Glycosylases Ogg1 and Nth1 Do Not Contribute to Ig Class Switching in Activated Mouse Splenic B Cells

Por Ucher, Anna J., Linehan, Erin K., Teebor, George W., Schrader, Carol E., Stavnezer, Janet
Publicado em 2012

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig loci in activated B cells

Por Staszewski, Ori, Baker, Richard E., Ucher, Anna J., Martier, Raygene, Stavnezer, Janet, Guikema, Jeroen E.J.
Publicado em 2011

AID binds cooperatively with UNG and Msh2-Msh6 to Ig switch regions dependent upon the AID C terminus()

Por Ranjit, Sanjay, Khair, Lyne, Linehan, Erin K., Ucher, Anna J., Chakrabarti, Mrinmay, Schrader, Carol E., Stavnezer, Janet
Publicado em 2011

Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation

Por Stavnezer, Janet, Linehan, Erin K., Thompson, Mikayla R., Habboub, Ghaith, Ucher, Anna J., Kadungure, Tatenda, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Schrader, Carol E.
Publicado em 2014

Mismatch repair proteins and AID deaminase activity are required for the dominant negative function of C terminally-deleted AID in class switching

Por Ucher, Anna J., Ranjit, Sanjay, Kadungure, Tatenda, Linehan, Erin K., Khair, Lyne, Xie, Elaine, Limauro, Jennifer, Rauch, Katherina S., Schrader, Carol E., Stavnezer, Janet
Publicado em 2014

ATM increases AID activity at downstream S regions during class switch recombination

Por Khair, Lyne, Guikema, Jeroen E.J., Linehan, Erin K., Ucher, Anna J., Leus, Niek G.J., Ogilvie, Colin, Lou, Zhenkun, Schrader, Carol E., Stavnezer, Janet
Publicado em 2014

A DNA break– and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination

Por Vuong, Bao Q, Herrick-Reynolds, Kayleigh, Vaidyanathan, Bharat, Pucella, Joseph N, Ucher, Anna J, Donghia, Nina M, Gu, Xiwen, Nicolas, Laura, Nowak, Urszula, Rahman, Numa, Strout, Matthew P, Mills, Kevin D, Stavnezer, Janet, Chaudhuri, Jayanta
Publicado em 2013