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AP-Endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge

B cell development involves rapid cellular proliferation, gene rearrangements, selection and differentiation, and provides a powerful model to study DNA repair processes in vivo. Analysis of the contribution of the base excision repair (BER) pathway in lymphocyte development has been lacking primari...

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Detalhes bibliográficos
Main Authors: Guikema, Jeroen E.J., Gerstein, Rachel M., Linehan, Erin K., Cloherty, Erin K., Evan-Browning, Eric, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Schrader, Carol E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041036/
https://ncbi.nlm.nih.gov/pubmed/21228350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002422
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