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A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase β

DNA repair is required to maintain genome stability in stem cells and early embryos. At critical junctures, oxidative damage to DNA requires the base excision repair (BER) pathway. Since early zebrafish embryos lack the major polymerase in BER, DNA polymerase ß, repair proceeds via replicative polym...

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Detalhes bibliográficos
Main Authors: Pei, De-Sheng, Yang, Xiao-Jie, Liu, Wei, Guikema, Jeroen E. J., Schrader, Carol E., Strauss, Phyllis R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082881/
https://ncbi.nlm.nih.gov/pubmed/21172930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1142
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