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A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase β
DNA repair is required to maintain genome stability in stem cells and early embryos. At critical junctures, oxidative damage to DNA requires the base excision repair (BER) pathway. Since early zebrafish embryos lack the major polymerase in BER, DNA polymerase ß, repair proceeds via replicative polym...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082881/ https://ncbi.nlm.nih.gov/pubmed/21172930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1142 |
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