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AP endonuclease 1 (Apex1) influences brain development linking oxidative stress and DNA repair
Brain and neurons are particularly sensitive to reactive oxygen species (ROS). Oxidative damage from ROS results in increased 8-oxoguanine in DNA followed by repair through the base excision repair (BER) pathway. We reported earlier that AP endonuclease 1 (Apex1) not only participates directly in BE...
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| Udgivet i: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484078/ https://ncbi.nlm.nih.gov/pubmed/31024003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1578-1 |
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