Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model

Although in vitro studies pointed to the tumor necrosis factor family member APRIL (a proliferation-inducing ligand) in mediating survival of chronic lymphocytic leukemia (CLL) cells, clear evidence for a role in leukemogenesis and progression in CLL is lacking. APRIL significantly prolonged in vitr...

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Autores principales: Lascano, Valeria, Guadagnoli, Marco, Schot, Jan G., Luijks, Dieuwertje M., Guikema, Jeroen E. J., Cameron, Katherine, Hahne, Michael, Pals, Steven, Slinger, Erik, Kipps, Thomas J., van Oers, Marinus H. J., Eldering, Eric, Medema, Jan Paul, Kater, Arnon P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2013
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123411/
https://ncbi.nlm.nih.gov/pubmed/24100449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-497693
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