Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing

Por Cristea, Sandra, Gregory, Philip D., Urnov, Fyodor D., Cost, Gregory J.
Publicado em 2011

Controlling long-range genomic interactions to reprogram the β-globin locus

Por Deng, Wulan, Rupon, Jeremy W, Wang, Hongxin, Reik, Andreas, Gregory, Philip D, Blobel, Gerd A
Publicado em 2013

Controlling long range genomic interactions at a native locus by targeted tethering of a looping factor

Por Deng, Wulan, Lee, Jongjoo, Wang, Hongxin, Miller, Jeff, Reik, Andreas, Gregory, Philip D., Dean, Ann, Blobel, Gerd A.
Publicado em 2012

Sticky collisions of ultracold RbCs molecules

Por Gregory, Philip D., Frye, Matthew D., Blackmore, Jacob A., Bridge, Elizabeth M., Sawant, Rahul, Hutson, Jeremy M., Cornish, Simon L.
Publicado no Nat Commun (2019)

Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome

Por Toscano, Miguel G., Anderson, Per, Muñoz, Pilar, Lucena, Gema, Cobo, Marién, Benabdellah, Karim, Gregory, Philip D., Holmes, Michael C., Martin, Francisco
Publicado em 2013

Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4(+) T Cell Resistance and Enrichment

Por Yuan, Jinyun, Wang, Jianbin, Crain, Karen, Fearns, Colleen, Kim, Kenneth A, Hua, Kevin L, Gregory, Philip D, Holmes, Michael C, Torbett, Bruce E
Publicado em 2012

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

Por Moehle, Erica A., Rock, Jeremy M., Lee, Ya-Li, Jouvenot, Yann, DeKelver, Russell C., Gregory, Philip D., Urnov, Fyodor D., Holmes, Michael C.
Publicado em 2007

Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery

Por Wang, Jianbin, DeClercq, Joshua J., Hayward, Samuel B., Li, Patrick Wai-Lun, Shivak, David A., Gregory, Philip D., Lee, Gary, Holmes, Michael C.
Publicado no Nucleic Acids Res (2016)

Reactivation of developmentally silenced globin genes by forced chromatin looping

Por Deng, Wulan, Rupon, Jeremy W., Krivega, Ivan, Breda, Laura, Motta, Irene, Jahn, Kristen S., Reik, Andreas, Gregory, Philip D., Rivella, Stefano, Dean, Ann, Blobel, Gerd A.
Publicado em 2014

Zinc finger nuclease-mediated CCR5 knockout hematopoietic stem cell transplantation controls HIV-1 in vivo

Por Holt, Nathalia, Wang, Jianbin, Kim, Kenneth, Friedman, Geoffrey, Wang, Xingchao, Taupin, Vanessa, Crooks, Gay M., Kohn, Donald B., Gregory, Philip D., Holmes, Michael C., Cannon, Paula M.
Publicado em 2010

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

Por Sexton, Alec N., Regalado, Samuel G., Lai, Christine S., Cost, Gregory J., O’Neil, Colleen M., Urnov, Fyodor D., Gregory, Philip D., Jaenisch, Rudolf, Collins, Kathleen, Hockemeyer, Dirk
Publicado em 2014

Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization

Por Leung, Wai-Hang, Gay, Joel, Martin, Unja, Garrett, Tracy E., Horton, Holly M., Certo, Michael T., Blazar, Bruce R., Morgan, Richard A., Gregory, Philip D., Jarjour, Jordan, Astrakhan, Alexander
Publicado no JCI Insight (2019)

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

Por Hauschild, Janet, Petersen, Bjoern, Santiago, Yolanda, Queisser, Anna-Lisa, Carnwath, Joseph W., Lucas-Hahn, Andrea, Zhang, Lei, Meng, Xiangdong, Gregory, Philip D., Schwinzer, Reinhard, Cost, Gregory J., Niemann, Heiner
Publicado em 2011

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

Por Wang, Jianbin, Friedman, Geoffrey, Doyon, Yannick, Wang, Nathaniel S., Li, Carrie Jiaxin, Miller, Jeffrey C., Hua, Kevin L., Yan, Jenny Jiacheng, Babiarz, Joshua E., Gregory, Philip D., Holmes, Michael C.
Publicado em 2012

Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine‐Releasing Capacity

Por Poppe, Daniel, Doerr, Jonas, Schneider, Marion, Wilkens, Ruven, Steinbeck, Julius A., Ladewig, Julia, Tam, Allison, Paschon, David E., Gregory, Philip D., Reik, Andreas, Müller, Christa E., Koch, Philipp, Brüstle, Oliver
Publicado no Stem Cells Transl Med (2018)

Site-Specific Editing of the Plasmodium falciparum Genome Using Engineered Zinc-Finger Nucleases

Por Straimer, Judith, Lee, Marcus CS, Lee, Andrew H, Zeitler, Bryan, Williams, April E, Pearl, Jocelynn R, Zhang, Lei, Rebar, Edward J, Gregory, Philip D, Llinás, Manuel, Urnov, Fyodor D, Fidock, David A
Publicado em 2012

An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Dis...

Por Laganiere, Josee, Kells, Adrian P., Lai, Jeffrey T., Guschin, Dmitry, Paschon, David E., Meng, Xiangdong, Fong, Lauren K., Yu, Qi, Rebar, Edward J., Gregory, Philip D., Bankiewicz, Krystof S., Forsayeth, John, Zhang, H. Steve
Publicado no J Neurosci (2010)

Efficient Immunoglobulin Gene Disruption and Targeted Replacement in Rabbit Using Zinc Finger Nucleases

Por Flisikowska, Tatiana, Thorey, Irmgard S., Offner, Sonja, Ros, Francesca, Lifke, Valeria, Zeitler, Bryan, Rottmann, Oswald, Vincent, Anna, Zhang, Lei, Jenkins, Shirin, Niersbach, Helmut, Kind, Alexander J., Gregory, Philip D., Schnieke, Angelika E., Platzer, Josef
Publicado em 2011

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

Por Simsek, Deniz, Brunet, Erika, Wong, Sunnie Yan-Wai, Katyal, Sachin, Gao, Yankun, McKinnon, Peter J., Lou, Jacqueline, Zhang, Lei, Li, James, Rebar, Edward J., Gregory, Philip D., Holmes, Michael C., Jasin, Maria
Publicado em 2011

Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell Model

Por Toscano, Miguel G, Muñoz, Pilar, Sánchez-Gilabert, Almudena, Cobo, Marién, Benabdellah, Karim, Anderson, Per, Ramos-Mejía, Verónica, Real, Pedro J, Neth, Olaf, Molinos-Quintana, Agueda, Gregory, Philip D, Holmes, Michael C, Martin, Francisco
Publicado no Mol Ther (2016)