CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

Por Billon, Pierre, Bryant, Eric E., Joseph, Sarah A., Nambiar, Tarun S., Hayward, Samuel B., Rothstein, Rodney, Ciccia, Alberto
Publicado no Mol Cell (2017)

Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery

Por Wang, Jianbin, DeClercq, Joshua J., Hayward, Samuel B., Li, Patrick Wai-Lun, Shivak, David A., Gregory, Philip D., Lee, Gary, Holmes, Michael C.
Publicado no Nucleic Acids Res (2016)

Homology-driven genome editing in hematopoietic stem and progenitor cells using zinc finger nuclease mRNA and AAV6 donors

Por Wang, Jianbin, Exline, Colin M., DeClercq, Joshua J., Llewellyn, G. Nicholas, Hayward, Samuel B., Li, Patrick Wai-Lun, Shivak, David A., Surosky, Richard T., Gregory, Philip D., Holmes, Michael C., Cannon, Paula M
Publicado no Nat Biotechnol (2015)

Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells

Por DiGiusto, David L, Cannon, Paula M, Holmes, Michael C, Li, Lijing, Rao, Anitha, Wang, Jianbin, Lee, Gary, Gregory, Philip D., Kim, Kenneth A, Hayward, Samuel B, Meyer, Kathleen, Exline, Colin, Lopez, Evan, Henley, Jill, Gonzalez, Nancy, Bedell, Victoria, Stan, Rodica, Zaia, John A
Publicado no Mol Ther Methods Clin Dev (2016)