CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

od Billon, Pierre, Bryant, Eric E., Joseph, Sarah A., Nambiar, Tarun S., Hayward, Samuel B., Rothstein, Rodney, Ciccia, Alberto
Wydane w Mol Cell (2017)

Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery

od Wang, Jianbin, DeClercq, Joshua J., Hayward, Samuel B., Li, Patrick Wai-Lun, Shivak, David A., Gregory, Philip D., Lee, Gary, Holmes, Michael C.
Wydane w Nucleic Acids Res (2016)

Functional interrogation of DNA damage response variants with base editing screens

od Cuella-Martin, Raquel, Hayward, Samuel B., Fan, Xiao, Chen, Xiao, Huang, Jen-Wei, Taglialatela, Angelo, Leuzzi, Giuseppe, Zhao, Junfei, Rabadan, Raul, Lu, Chao, Shen, Yufeng, Ciccia, Alberto
Wydane w Cell (2021)

Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant

od Nambiar, Tarun S., Billon, Pierre, Diedenhofen, Giacomo, Hayward, Samuel B., Taglialatela, Angelo, Cai, Kunheng, Huang, Jen-Wei, Leuzzi, Giuseppe, Cuella-Martin, Raquel, Palacios, Andrew, Gupta, Anuj, Egli, Dieter, Ciccia, Alberto
Wydane w Nat Commun (2019)

Homology-driven genome editing in hematopoietic stem and progenitor cells using zinc finger nuclease mRNA and AAV6 donors

od Wang, Jianbin, Exline, Colin M., DeClercq, Joshua J., Llewellyn, G. Nicholas, Hayward, Samuel B., Li, Patrick Wai-Lun, Shivak, David A., Surosky, Richard T., Gregory, Philip D., Holmes, Michael C., Cannon, Paula M
Wydane w Nat Biotechnol (2015)

MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage

od Huang, Jen-Wei, Acharya, Ananya, Taglialatela, Angelo, Nambiar, Tarun S., Cuella-Martin, Raquel, Leuzzi, Giuseppe, Hayward, Samuel B., Joseph, Sarah A., Brunette, Gregory J., Anand, Roopesh, Soni, Rajesh K., Clark, Nathan L., Bernstein, Kara A., Cejka, Petr, Ciccia, Alberto
Wydane w Nat Commun (2020)

Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures

od Billon, Pierre, Nambiar, Tarun S., Hayward, Samuel B., Zafra, Maria P., Schatoff, Emma M., Oshima, Koichi, Dunbar, Andrew, Breinig, Marco, Park, Young C., Ryu, Han S., Tschaharganeh, Darjus F., Levine, Ross L., Baer, Richard, Ferrando, Adolfo, Dow, Lukas E., Ciccia, Alberto
Wydane w Cell Rep (2020)

Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells

od DiGiusto, David L, Cannon, Paula M, Holmes, Michael C, Li, Lijing, Rao, Anitha, Wang, Jianbin, Lee, Gary, Gregory, Philip D., Kim, Kenneth A, Hayward, Samuel B, Meyer, Kathleen, Exline, Colin, Lopez, Evan, Henley, Jill, Gonzalez, Nancy, Bedell, Victoria, Stan, Rodica, Zaia, John A
Wydane w Mol Ther Methods Clin Dev (2016)