Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures

Genome editing technologies have transformed our ability to engineer desired genomic changes within living systems. However, detecting precise genomic modifications often requires sophisticated, expensive, and time-consuming experimental approaches. Here, we describe DTECT (Dinucleotide signaTurE Ca...

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Pubblicato in:Cell Rep
Autori principali: Billon, Pierre, Nambiar, Tarun S., Hayward, Samuel B., Zafra, Maria P., Schatoff, Emma M., Oshima, Koichi, Dunbar, Andrew, Breinig, Marco, Park, Young C., Ryu, Han S., Tschaharganeh, Darjus F., Levine, Ross L., Baer, Richard, Ferrando, Adolfo, Dow, Lukas E., Ciccia, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108696/
https://ncbi.nlm.nih.gov/pubmed/32160537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.068
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