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Inducible in vivo genome editing with CRISPR/Cas9
CRISPR/Cas9-based genome editing enables the rapid genetic manipulation of any genomic locus without the need for gene targeting by homologous recombination. Here we describe a conditional transgenic approach that allows temporal control of CRISPR/Cas9 activity for inducible genome editing in adult...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390466/ https://ncbi.nlm.nih.gov/pubmed/25690852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3155 |
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