Inducible in vivo genome editing with CRISPR/Cas9

CRISPR/Cas9-based genome editing enables the rapid genetic manipulation of any genomic locus without the need for gene targeting by homologous recombination. Here we describe a conditional transgenic approach that allows temporal control of CRISPR/Cas9 activity for inducible genome editing in adult...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Biotechnol
Main Authors: Dow, Lukas E, Fisher, Jonathan, O'Rourke, Kevin P, Muley, Ashlesha, Kastenhuber, Edward R, Livshits, Geulah, Tschaharganeh, Darjus F, Socci, Nicholas D, Lowe, Scott W
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390466/
https://ncbi.nlm.nih.gov/pubmed/25690852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3155
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker