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Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures

Genome editing technologies have transformed our ability to engineer desired genomic changes within living systems. However, detecting precise genomic modifications often requires sophisticated, expensive, and time-consuming experimental approaches. Here, we describe DTECT (Dinucleotide signaTurE Ca...

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Vydáno v:Cell Rep
Hlavní autoři: Billon, Pierre, Nambiar, Tarun S., Hayward, Samuel B., Zafra, Maria P., Schatoff, Emma M., Oshima, Koichi, Dunbar, Andrew, Breinig, Marco, Park, Young C., Ryu, Han S., Tschaharganeh, Darjus F., Levine, Ross L., Baer, Richard, Ferrando, Adolfo, Dow, Lukas E., Ciccia, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108696/
https://ncbi.nlm.nih.gov/pubmed/32160537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.068
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