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Controlling long range genomic interactions at a native locus by targeted tethering of a looping factor
Chromatin loops juxtapose distal enhancers with active promoters but their molecular architecture and relationship with transcription remain unclear. In erythroid cells, the locus control region (LCR) and β-globin promoter form a chromatin loop that requires transcription factor GATA1 and the associ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372860/ https://ncbi.nlm.nih.gov/pubmed/22682246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.051 |
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