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Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus

Enhancers can regulate designate promoters over long distances by forming chromatin loops. Whether chromatin loops are lost or reconfigured during gene repression is largely unexplored. We examined the chromosome conformation of the Kit gene that is expressed during early erythropoiesis, but is down...

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Detalles Bibliográficos
Main Authors: Jing, Huie, Vakoc, Christopher R., Ying, Lei, Mandat, Sean, Wang, Hongxin, Zheng, Xingwu, Blobel, Gerd A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254447/
https://ncbi.nlm.nih.gov/pubmed/18243117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.020
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