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Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus
Enhancers can regulate designate promoters over long distances by forming chromatin loops. Whether chromatin loops are lost or reconfigured during gene repression is largely unexplored. We examined the chromosome conformation of the Kit gene that is expressed during early erythropoiesis, but is down...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254447/ https://ncbi.nlm.nih.gov/pubmed/18243117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.020 |
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