Control of telomerase action at human telomeres

Por Hockemeyer, Dirk, Collins, Kathleen
Publicado no Nat Struct Mol Biol (2015)

Induced pluripotent stem cells meet genome editing

Por Hockemeyer, Dirk, Jaenisch, Rudolf
Publicado no Cell Stem Cell (2016)

TALEN gene knockouts reveal no requirement for the conserved human shelterin protein Rap1 in telomere protection and length regulation

Por Kabir, Shaheen, Hockemeyer, Dirk, de Lange, Titia
Publicado no Cell Rep (2014)

Genetically-engineered human cortical spheroid models of Tuberous Sclerosis

Por Blair, John D., Hockemeyer, Dirk, Bateup, Helen S.
Publicado no Nat Med (2018)

Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation

Por Blair, John D., Bateup, Helen S., Hockemeyer, Dirk F.
Publicado no J Vis Exp (2016)

Functional Dissection of Human and Mouse POT1 Proteins

Por Palm, Wilhelm, Hockemeyer, Dirk, Kibe, Tatsuya, de Lange, Titia
Publicado em 2009

SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development

Por Schratt, Gerhard, Philippar, Ulrike, Hockemeyer, Dirk, Schwarz, Heinz, Alberti, Siegfried, Nordheim, Alfred
Publicado em 2004

Engineered telomere degradation models dyskeratosis congenita

Por Hockemeyer, Dirk, Palm, Wilhelm, Wang, Richard C., Couto, Suzana S., de Lange, Titia
Publicado em 2008

Analysis of muntjac deer genome and chromatin architecture reveals rapid karyotype evolution

Por Mudd, Austin B., Bredeson, Jessen V., Baum, Rachel, Hockemeyer, Dirk, Rokhsar, Daniel S.
Publicado no Commun Biol (2020)

A drug-inducible system for direct reprogramming of human somatic cells to pluripotency

Por Hockemeyer, Dirk, Soldner, Frank, Cook, Elizabeth G., Gao, Qing, Mitalipova, Maisam, Jaenisch, Rudolf
Publicado em 2008

Widespread translational remodeling during human neuronal differentiation

Por Blair, John D., Hockemeyer, Dirk, Doudna, Jennifer A., Bateup, Helen S., Floor, Stephen N.
Publicado no Cell Rep (2017)

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

Por Hockemeyer, Dirk, Sfeir, Agnel J, Shay, Jerry W, Wright, Woodring E, de Lange, Titia
Publicado em 2005

Transgene Excision Has No Impact on In Vivo Integration of Human iPS Derived Neural Precursors

Por Major, Tamara, Menon, Jayanthi, Auyeung, Gordon, Soldner, Frank, Hockemeyer, Dirk, Jaenisch, Rudolf, Tabar, Viviane
Publicado em 2011

Cancer-associated TERT promoter mutations abrogate telomerase silencing

Por Chiba, Kunitoshi, Johnson, Joshua Z, Vogan, Jacob M, Wagner, Tina, Boyle, John M, Hockemeyer, Dirk
Publicado no eLife (2015)

Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo

Por Chiba, Kunitoshi, Vogan, Jacob M., Wu, Robert A., Gill, Manraj S., Zhang, Xiaozhu, Collins, Kathleen, Hockemeyer, Dirk
Publicado no Mol Cell Biol (2017)

4D cell biology: big data image analytics and lattice light-sheet imaging reveal dynamics of clathrin-mediated endocytosis in stem cell–derived intestinal organoids

Por Schöneberg, Johannes, Dambournet, Daphné, Liu, Tsung-Li, Forster, Ryan, Hockemeyer, Dirk, Betzig, Eric, Drubin, David G.
Publicado no Mol Biol Cell (2018)

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

Por Guenther, Matthew G., Frampton, Garrett M., Soldner, Frank, Hockemeyer, Dirk, Mitalipova, Maya, Jaenisch, Rudolf, Young, Richard A.
Publicado em 2010

Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies

Por Vogan, Jacob M, Zhang, Xiaozhu, Youmans, Daniel T, Regalado, Samuel G, Johnson, Joshua Z, Hockemeyer, Dirk, Collins, Kathleen
Publicado no eLife (2016)

Genome-edited human stem cells expressing fluorescently labeled endocytic markers allow quantitative analysis of clathrin-mediated endocytosis during differentiation

Por Dambournet, Daphné, Sochacki, Kem A., Cheng, Aaron T., Akamatsu, Matthew, Taraska, Justin W., Hockemeyer, Dirk, Drubin, David G.
Publicado no J Cell Biol (2018)

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

Por Sfeir, Agnel, Kosiyatrakul, Settapong T., Hockemeyer, Dirk, MacRae, Sheila L., Karlseder, Jan, Schildkraut, Carl L., de Lange, Titia
Publicado em 2009