Repressive Transcription

Por Guenther, Matthew G., Young, Richard A.
Publicado em 2010

The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

Por Guenther, Matthew G., Barak, Orr, Lazar, Mitchell A.
Publicado em 2001

Proteasomal regulation of nuclear receptor corepressor-mediated repression

Por Zhang, Jinsong, Guenther, Matthew G., Carthew, Richard W., Lazar, Mitchell A.
Publicado em 1998

A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation

Por Yu, Jiujiu, Li, Yun, Ishizuka, Takahiro, Guenther, Matthew G., Lazar, Mitchell A.
Publicado em 2003

CpG Island Structure and Trithorax/Polycomb Chromatin Domains in Human Cells

Por Orlando, David A., Guenther, Matthew G., Frampton, Garrett M., Young, Richard A.
Publicado em 2012

A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells

Por Guenther, Matthew G., Levine, Stuart S., Boyer, Laurie A., Jaenisch, Rudolf, Young, Richard A.
Publicado em 2007

Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex

Por Guenther, Matthew G., Yu, Jiujiu, Kao, Gary D., Yen, Tim J., Lazar, Mitchell A.
Publicado em 2002

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

Por Guenther, Matthew G., Lane, William S., Fischle, Wolfgang, Verdin, Eric, Lazar, Mitchell A., Shiekhattar, Ramin
Publicado em 2000

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

Por Huang, Eric Y., Zhang, Jinsong, Miska, Eric A., Guenther, Matthew G., Kouzarides, Tony, Lazar, Mitchell A.
Publicado em 2000

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

Por Guenther, Matthew G., Frampton, Garrett M., Soldner, Frank, Hockemeyer, Dirk, Mitalipova, Maya, Jaenisch, Rudolf, Young, Richard A.
Publicado em 2010

Global and Hox-specific roles for the MLL1 methyltransferase

Por Guenther, Matthew G., Jenner, Richard G., Chevalier, Brett, Nakamura, Tatsuya, Croce, Carlo M., Canaani, Eli, Young, Richard A.
Publicado em 2005

Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response

Por Kao, Gary D., McKenna, W. Gillies, Guenther, Matthew G., Muschel, Ruth J., Lazar, Mitchell A., Yen, Tim J.
Publicado em 2003

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

Por Guenther, Matthew G., Lawton, Lee N., Rozovskaia, Tatiana, Frampton, Garrett M., Levine, Stuart S., Volkert, Thomas L., Croce, Carlo M., Nakamura, Tatsuya, Canaani, Eli, Young, Richard A.
Publicado em 2008

Evidence That Gene Activation and Silencing during Stem Cell Differentiation Requires a Transcriptionally Paused Intermediate State

Por Golob, Jonathan L., Kumar, Roshan M., Guenther, Matthew G., Pabon, Lil M., Pratt, Gabriel A., Loring, Jeanne F., Laurent, Louise C., Young, Richard A., Murry, Charles E.
Publicado em 2011

Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling

Por Mullen, Alan C., Orlando, David A., Newman, Jamie J., Lovén, Jakob, Kumar, Roshan M., Bilodeau, Steve, Reddy, Jessica, Guenther, Matthew G., DeKoter, Rodney, Young, Richard A.
Publicado em 2011

Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

Por Sigova, Alla A., Mullen, Alan C., Molinie, Benoit, Gupta, Sumeet, Orlando, David A., Guenther, Matthew G., Almada, Albert E., Lin, Charles, Sharp, Phillip A., Giallourakis, Cosmas C., Young, Richard A.
Publicado em 2013

Genome-wide determination of drug localization

Por Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J., Rahl, Peter B., Lovén, Jakob, Sigova, Alla A., Smith, William B., Lee, Tong Ihn, Bradner, James E., Young, Richard A.
Publicado em 2013

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Por Boyer, Laurie A., Lee, Tong Ihn, Cole, Megan F., Johnstone, Sarah E., Levine, Stuart S., Zucker, Jacob P., Guenther, Matthew G., Kumar, Roshan M., Murray, Heather L., Jenner, Richard G., Gifford, David K., Melton, Douglas A., Jaenisch, Rudolf, Young, Richard A.
Publicado em 2005

Super-Enhancer analysis defines novel epigenomic subtypes of non-APL AML including an RARα dependency targetable by SY-1425, a potent and selective RARα agonist

Por McKeown, Michael R, Corces, M. Ryan, Eaton, Matthew L, Fiore, Chris, Lee, Emily, Lopez, Jeremy T, Chen, Mei Wei, Smith, Darren, Chan, Steven M., Koenig, Julie L., Austgen, Kathryn, Guenther, Matthew G, Orlando, David A., Lovén, Jakob, Fritz, Christian C, Majeti, Ravindra
Publicado no Cancer Discov (2017)

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

Por Marson, Alexander, Levine, Stuart S., Cole, Megan F., Frampton, Garrett M., Brambrink, Tobias, Johnstone, Sarah, Guenther, Matthew G., Johnston, Wendy K., Wernig, Marius, Newman, Jamie, Calabrese, J. Mauro, Dennis, Lucas M., Volkert, Thomas L., Gupta, Sumeet, Love, Jennifer, Hannett, Nancy, Sharp, Phillip A., Bartel, David P., Jaenisch, Rudolf, Young, Richard A.
Publicado em 2008