Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

MicroRNAs (miRNAs) are crucial for normal embryonic stem (ES) cell self-renewal and cellular differentiation, but how miRNA gene expression is controlled by the key transcriptional regulators of ES cells has not been established. We describe here a new map of the transcriptional regulatory circuitry...

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Bibliographische Detailangaben
Hauptverfasser: Marson, Alexander, Levine, Stuart S., Cole, Megan F., Frampton, Garrett M., Brambrink, Tobias, Johnstone, Sarah, Guenther, Matthew G., Johnston, Wendy K., Wernig, Marius, Newman, Jamie, Calabrese, J. Mauro, Dennis, Lucas M., Volkert, Thomas L., Gupta, Sumeet, Love, Jennifer, Hannett, Nancy, Sharp, Phillip A., Bartel, David P., Jaenisch, Rudolf, Young, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586071/
https://ncbi.nlm.nih.gov/pubmed/18692474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.07.020
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