Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

The transcription factors OCT4, SOX2, and NANOG have essential roles in early development and are required for the propagation of undifferentiated embryonic stem (ES) cells in culture. To gain insights into transcriptional regulation of human ES cells, we have identified OCT4, SOX2, and NANOG target...

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Detalhes bibliográficos
Main Authors: Boyer, Laurie A., Lee, Tong Ihn, Cole, Megan F., Johnstone, Sarah E., Levine, Stuart S., Zucker, Jacob P., Guenther, Matthew G., Kumar, Roshan M., Murray, Heather L., Jenner, Richard G., Gifford, David K., Melton, Douglas A., Jaenisch, Rudolf, Young, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006442/
https://ncbi.nlm.nih.gov/pubmed/16153702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.08.020
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