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Transgene Excision Has No Impact on In Vivo Integration of Human iPS Derived Neural Precursors

The derivation of induced human pluripotent stem cells (hiPS) has generated significant enthusiasm particularly for the prospects of cell-based therapy. But there are concerns about the suitability of iPS cells for in vivo applications due in part to the introduction of potentially oncogenic transcr...

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Bibliografski detalji
Glavni autori: Major, Tamara, Menon, Jayanthi, Auyeung, Gordon, Soldner, Frank, Hockemeyer, Dirk, Jaenisch, Rudolf, Tabar, Viviane
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178523/
https://ncbi.nlm.nih.gov/pubmed/21961042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024687
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