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Site-Specific Editing of the Plasmodium falciparum Genome Using Engineered Zinc-Finger Nucleases
Malaria afflicts over 200 million people worldwide and its most lethal etiologic agent, Plasmodium falciparum, is evolving to resist even the latest-generation therapeutics. Efficient tools for genome-directed investigations of P. falciparum pathogenesis, including drug resistance mechanisms, are cl...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697006/ https://ncbi.nlm.nih.gov/pubmed/22922501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2143 |
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