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Editing the Plasmodium vivax Genome, Using Zinc-Finger Nucleases
Plasmodium vivax is a major cause of malaria morbidity worldwide yet has remained genetically intractable. To stably modify this organism, we used zinc-finger nucleases (ZFNs), which take advantage of homology-directed DNA repair mechanisms at the site of nuclease action. Using ZFNs specific to the...
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Vydáno v: | J Infect Dis |
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Hlavní autoři: | , , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Oxford University Press
2015
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334824/ https://ncbi.nlm.nih.gov/pubmed/25081932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu423 |
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