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Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs)

Genome editing is a powerful technique that can be used to elucidate gene function and the genetic basis of disease. Traditional gene editing methods such as chemical-based mutagenesis or random integration of DNA sequences confer indiscriminate genetic changes in an overall inefficient manner and r...

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Detalhes bibliográficos
Main Authors: Hansen, Keith, Coussens, Matthew J., Sago, Jack, Subramanian, Shilpi, Gjoka, Monika, Briner, Dave
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476380/
https://ncbi.nlm.nih.gov/pubmed/22732945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3304
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