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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are specific for nearly any site in the genome. These domains can be treated as modular units and assembled to create a polydacty...

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Detalhes bibliográficos
Main Authors: Mandell, Jeffrey G., Barbas, Carlos F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538883/
https://ncbi.nlm.nih.gov/pubmed/16845061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl209
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