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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are specific for nearly any site in the genome. These domains can be treated as modular units and assembled to create a polydacty...

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Bibliografiske detaljer
Main Authors: Mandell, Jeffrey G., Barbas, Carlos F.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538883/
https://ncbi.nlm.nih.gov/pubmed/16845061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl209
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