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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are specific for nearly any site in the genome. These domains can be treated as modular units and assembled to create a polydacty...

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書目詳細資料
Main Authors: Mandell, Jeffrey G., Barbas, Carlos F.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538883/
https://ncbi.nlm.nih.gov/pubmed/16845061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl209
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