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Custom-designed zinc finger nucleases: What is next?
Custom-designed zinc finger nucleases (ZFNs) – proteins designed to cut at specific DNA sequences – combine the non-specific cleavage domain (N) of Fok I restriction endonuclease with zinc finger proteins (ZFPs). Because the recognition specificities of the ZFPs can be easily manipulated experimenta...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921987/ https://ncbi.nlm.nih.gov/pubmed/17763826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-007-7206-8 |
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