Generation and Genetic Engineering of Human Induced Pluripotent Stem Cells Using Designed Zinc Finger Nucleases

Zinc finger nucleases (ZFNs) have become powerful tools to deliver a targeted double-strand break at a pre-determined chromosomal locus in order to insert an exogenous transgene by homology-directed repair. ZFN-mediated gene targeting was used to generate both single-allele chemokine (C-C motif) rec...

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Detalhes bibliográficos
Main Authors: Ramalingam, Sivaprakash, London, Viktoriya, Kandavelou, Karthikeyan, Cebotaru, Liudmila, Guggino, William, Civin, Curt, Chandrasegaran, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565436/
https://ncbi.nlm.nih.gov/pubmed/22931452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0245
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