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Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells
Custom-designed zinc finger nucleases (ZFNs), proteins designed to cut at specific DNA sequences, are becoming powerful tools in gene targeting—the process of replacing a gene within a genome by homologous recombination (HR). ZFNs that combine the non-specific cleavage domain (N) of FokI endonucleas...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1270952/ https://ncbi.nlm.nih.gov/pubmed/16251401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki912 |
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