Editing the Plasmodium vivax Genome, Using Zinc-Finger Nucleases

Plasmodium vivax is a major cause of malaria morbidity worldwide yet has remained genetically intractable. To stably modify this organism, we used zinc-finger nucleases (ZFNs), which take advantage of homology-directed DNA repair mechanisms at the site of nuclease action. Using ZFNs specific to the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Infect Dis
Egile Nagusiak: Moraes Barros, Roberto R., Straimer, Judith, Sa, Juliana M., Salzman, Rebecca E., Melendez-Muniz, Viviana A., Mu, Jianbing, Fidock, David A., Wellems, Thomas E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2015
Gaiak:
Major Articles and Brief Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334824/
https://ncbi.nlm.nih.gov/pubmed/25081932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu423
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