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CRISPR-mediated genome editing of Plasmodium falciparum malaria parasites

The development of the CRISPR-Cas system is revolutionizing genome editing in a variety of organisms. The system has now been used to manipulate the genome of Plasmodium falciparum, the most lethal malaria-causing species. The ability to generate gene deletions or nucleotide substitutions rapidly an...

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Bibliografiske detaljer
Udgivet i:Genome Med
Main Authors: Lee, Marcus CS, Fidock, David A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254425/
https://ncbi.nlm.nih.gov/pubmed/25473431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0063-9
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