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PEST sequences in the malaria parasite Plasmodium falciparum: a genomic study

BACKGROUND: Inhibitors of the protease calpain are known to have selectively toxic effects on Plasmodium falciparum. The enzyme has a natural inhibitor calpastatin and in eukaryotes is responsible for turnover of proteins containing short sequences enriched in certain amino acids (PEST sequences). T...

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Detalhes bibliográficos
Main Authors: Mitchell, David, Bell, Angus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC198282/
https://ncbi.nlm.nih.gov/pubmed/12857354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-2-16
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