DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

Nonhomologous end-joining (NHEJ) is the primary DNA repair pathway thought to underlie chromosomal translocations and other genomic rearrangements in somatic cells. The canonical NHEJ pathway, including DNA ligase IV (Lig4), suppresses genomic instability and chromosomal translocations, leading to t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Simsek, Deniz, Brunet, Erika, Wong, Sunnie Yan-Wai, Katyal, Sachin, Gao, Yankun, McKinnon, Peter J., Lou, Jacqueline, Zhang, Lei, Li, James, Rebar, Edward J., Gregory, Philip D., Holmes, Michael C., Jasin, Maria
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107202/
https://ncbi.nlm.nih.gov/pubmed/21655080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002080
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