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Nonhomologous DNA End Joining (NHEJ) and Chromosomal Translocations in Humans
Estimates are that double-strand breaks (DSBs) arise in dividing cells about ten times per cell per day. Causes include replication across a nick, free radicals of oxidative metabolism, ionizing radiation, and inadvertent action by enzymes of DNA metabolism (such as failures of type II topoisomerase...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079314/ https://ncbi.nlm.nih.gov/pubmed/20012587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-90-481-3471-7_14 |
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