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Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases
Efficient incorporation of novel DNA sequences into a specific site in the genome of living human cells remains a challenge despite its potential utility to genetic medicine, biotechnology, and basic research. We find that a precisely placed double-strand break induced by engineered zinc finger nucl...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1802009/ https://ncbi.nlm.nih.gov/pubmed/17360608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611478104 |
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