Progress in Top-Down Proteomics and the Analysis of Proteoforms

由 Toby, Timothy K., Fornelli, Luca, Kelleher, Neil L.
發表在 Annu Rev Anal Chem (Palo Alto Calif) (2016)

Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype

由 Doubleday, Peter F., Fornelli, Luca, Kelleher, Neil L.
發表在 J Proteome Res (2020)

Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry

由 Compton, Philip D., Fornelli, Luca, Kelleher, Neil L., Skinner, Owen S.
發表在 Int J Mass Spectrom (2015)

The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics

由 Lyon, Yana A., Riggs, Dylan, Fornelli, Luca, Compton, Philip D., Julian, Ryan R.
發表在 J Am Soc Mass Spectrom (2017)

Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite

由 DeHart, Caroline J., Fellers, Ryan T., Fornelli, Luca, Kelleher, Neil L., Thomas, Paul M.
發表在 Methods Mol Biol (2017)

Chromatographic Efficiency and Selectivity in Top-down Proteomics of Histones

由 Zhou, Yiyang, Zhang, Ximo, Fornelli, Luca, Compton, Philip D., Kelleher, Neil, Wirth, Mary J.
發表在 J Chromatogr B Analyt Technol Biomed Life Sci (2016)

Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa

由 Durbin, Kenneth R., Fornelli, Luca, Fellers, Ryan T., Doubleday, Peter F., Narita, Masashi, Kelleher, Neil L.
發表在 J Proteome Res (2016)

Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics

由 Melani, Rafael D., Skinner, Owen S., Fornelli, Luca, Domont, Gilberto B., Compton, Philip D., Kelleher, Neil L.
發表在 Mol Cell Proteomics (2016)

A comprehensive pipeline for translational top-down proteomics from a single blood draw

由 Toby, Timothy K., Fornelli, Luca, Srzentić, Kristina, DeHart, Caroline J., Levitsky, Josh, Friedewald, John, Kelleher, Neil L.
發表在 Nat Protoc (2019)

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

由 Fornelli, Luca, Damoc, Eugen, Thomas, Paul M., Kelleher, Neil L., Aizikov, Konstantin, Denisov, Eduard, Makarov, Alexander, Tsybin, Yury O.
出版 2012

Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry

由 Melani, Rafael D., Srzentić, Kristina, Gerbasi, Vincent R., McGee, John P., Huguet, Romain, Fornelli, Luca, Kelleher, Neil L.
發表在 MAbs (2019)

Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry

由 Savaryn, John Paul, Skinner, Owen S., Fornelli, Luca, Fellers, Ryan T., Compton, Philip D., Terhune, Scott S., Abecassis, Mike M., Kelleher, Neil L.
發表在 J Proteomics (2015)

Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer

由 Fornelli, Luca, Ayoub, Daniel, Aizikov, Konstantin, Liu, Xiaowen, Damoc, Eugen, Pevzner, Pavel A., Makarov, Alexander, Beck, Alain, Tsybin, Yury O.
發表在 J Proteomics (2017)

Top-down proteomics: where we are, where we are going?

由 Fornelli, Luca, Toby, Timothy K., Schachner, Luis F., Doubleday, Peter F., Srzentić, Kristina, DeHart, Caroline J., Kelleher, Neil L.
發表在 J Proteomics (2017)

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding

由 Huang, Xiaoxiao, LeDuc, Richard D., Fornelli, Luca, Schunter, Alissa J., Bennett, Richard L., Kelleher, Neil L., Licht, Jonathan D.
發表在 J Biol Chem (2019)

Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms

由 Huguet, Romain, Mullen, Christopher, Srzentić, Kristina, Greer, Joseph B., Fellers, Ryan T., Zabrouskov, Vlad, Syka, John E. P., Kelleher, Neil L., Fornelli, Luca
發表在 Anal Chem (2019)

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer

由 Fornelli, Luca, Durbin, Kenneth R., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., LeDuc, Richard D., Compton, Philip D., Kelleher, Neil L.
發表在 J Proteome Res (2016)

Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques

由 Fornelli, Luca, Srzentić, Kristina, Huguet, Romain, Mullen, Christopher, Sharma, Seema, Zabrouskov, Vlad, Fellers, Ryan T., Durbin, Kenneth R., Compton, Philip D., Kelleher, Neil L.
發表在 Anal Chem (2018)

Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry

由 van der Burgt, Yuri E.M., Kilgour, David P. A., Tsybin, Yury O., Srzentić, Kristina, Fornelli, Luca, Beck, Alain, Wuhrer, Manfred, Nicolardi, Simone
發表在 Anal Chem (2018)

Defining gas-phase fragmentation propensities of intact proteins during native top-down mass spectrometry

由 Haverland, Nicole A., Skinner, Owen S., Fellers, Ryan T., Tariq, Areeba A., Early, Bryan P., LeDuc, Richard D., Fornelli, Luca, Compton, Philip D., Kelleher, Neil L.
發表在 J Am Soc Mass Spectrom (2017)