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Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite

Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids long). In top-down proteomics, proteins remain intact and are directly measured within the mass spectrometer. This technique, while inhere...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: DeHart, Caroline J., Fellers, Ryan T., Fornelli, Luca, Kelleher, Neil L., Thomas, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373093/
https://ncbi.nlm.nih.gov/pubmed/28150248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6783-4_18
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